Total Syntheses of Balsacone B and Balsacone C

Total syntheses of (-)-huperzine Q and (+)-lycopladines B and C.

Utilizing a late-stage enamine bromofunctionalization strategy, the twelve-step total synthesis of (-)-huperzine Q was accomplished. Furthermore, the first total syntheses of (+)-lycopladines B and C are described. An unprecedented X-ray crystal structure of an unusual epoxyamine intermediate is also reported, and the synthetic application of this intermediate in natural product synthesis is de...

Total syntheses of amythiamicins A, B and C.

Total syntheses of the thiopeptide antibiotics amythiamicins A, B and C are reported.

Callipeltosides A, B and C: Total Syntheses and Structural Confirmation

Since their isolation almost 20 years ago, the callipeltosides have been of long standing interest to the synthetic community owing to their unique structural features and inherent biological activity. Herein we present our full research effort that has led to the synthesis of these molecules. Key aspects of our final strategy include 1) synthesis of the C1-C9 pyran core (5) using an AuCl3 -cat...

Total syntheses of subereamollines A and B.

The first total syntheses of (+)- and (-)-subereamollines A and B are reported. The enantiomeric forms of the natural products were obtained by preparative chiral HPLC separation of the corresponding racemates.

Total syntheses of dalesconol A and B.